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Clomifene is a selective oestrogen receptor modulator that has both oestrogenic and antioestrogenic properties. Clomiphene is used to induce ovulation (egg production) in women who do not produce ova (eggs) but wish to become pregnant (infertility). Clomiphene citrate initiates a series of endocrine events culminating in a preovulatory gonadotropin surge and subsequent follicular rupture. Clomiphene is a selective estrogen receptor modulator (serm). It selectively binds to estrogen receptors in the. It acts as a selective estrogen receptor modulator (serm), similar to tamoxifen and raloxifene. All three drugs are competitive inhibitors of. For some years clomiphene has been used to induce ovulation in anovulatory patients (g r e e n b 1 a t t,. However, the mechanism of its action is. Clomifene appears to stumulate the release of gonadotropins, follicle-stimulating hormone (fsh), and leuteinizing hormone (lh), which leads to the development. Clomifene, also known as clomiphene, is a medication used to treat infertility in women who do not ovulate, including those with polycystic ovary syndrome
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